基本情况
姓名：万一千
性别：男
籍贯：暂未填写
职位：
博士，教授，博士生导师
联系方式
电话：电 话：+86-020-84110918 手机：13535191168
传真：暂未填写
通讯地址：广东省广州市明星色情小说 化学与化学工程学院
邮编：510275
个人网站：暂未填写
教育经历
1980年9月—1984年7月，湖南师范大学，学士学位；
1984年7月—1989年9月，湖南省常德卫生学校， 教师；
1989年9月—1992年7月， 南开大学， 硕士学位，导师：周秀中教授；
1992年9月—1995年7月， 明星色情小说
， 博士学位，导师：曾陇梅教授。
工作经历
1995年7月—1998年8月，明星色情小说
化学系，1997年晋升副教授，从事天然产物化学的研究，参与国家自然科学基金和广东省基金的课题的研究。
1998年9月—1999年2月在香港津会大学化学系作访问研究，从事有机传感器的研究。
1999年3月—2000年2月在LUND大学有机化学和生物有机化学系访问研究，从事手性催化剂配体活性天然产物全合成的研究。
2000年3月—2000年9月在明星色情小说
化学院工作。
2000年9月—2003年1月在瑞典UPPSALA大学生物医药中心有机药物化学系作博士后研究。研究的方向是药物设计与合成；微波辅助快速反应方法学研究。
2003年2月—2013年1月，明星色情小说
化学与化学工程学院，副教授。
2013年1月—现在，明星色情小说
化学与化学工程学院教授。
讲授课程
现代化学研究方法与技术（化院硕士必修），有机合成新方法与新技术（有机硕士必修），有机分离与结构分析（有机硕士必修），药物设计与药物化学（硕士选修），药物化学（化院本科选、必修），天然产物研究方法（有机硕士选修）。
科研方向
暂无资料
科研项目
1. 海洋生物活性物质和中药有效成分的分离、结构测定或作为抗肿瘤、抗艾滋病药物及老年病和代病治疗药物的研究（国家863基金资助）；
2. 高选择性PDEs抑制剂的设计与合成（中大校基金资助）；
3. 新型AT2受体选择性激动剂的设计与合成；
4. 微波辅助绿色化学与催化（国家基金资助） 。
获奖情况
暂无资料
论著一览
1. Xinhai Zhu, Li Su, Liye Huang, Gong Chen, Jinlong Wang, Huacan Song, and Yi-qian Wan*, A Facile and Efficient Oxalyldihydrazide/Ketone-Promoted Copper-Catalyzed Amination of Aryl Halides in Water, Eur. J. Org. Chem., 2009, 635–642.
2. Yi, Wei; Cao, Rihui; Wen, Huan; Yan, Qin; Zhou, Binhua; Yi-qian Wan; Ma, Lin; Song, Huacan. Synthesis and biological evaluation of helicid analogues as mushroom tyrosinase inhibitors. Bioorganic & Medicinal Chemistry Letters (2008), 18(24), 6490-6493.
3. 刘进兵，林崇懒，万一千，宋化灿*，1,5-苯并二氮杂卓的合成及其生物活性研究，有机化学，2008, 28(2), 317-320.
4. Zhi Qiang Gao,a Bao Xiu Mi,*ae Gui Zhen Xu,c Yi-qian Wan,c Meng Lian Gong,c Kok Wai Cheahab and Chin H.Chend Chem. Commun., 2008, 117–119.
5. Wu, Peng; Yi-qian Wan; Cai, Jiwen*. Carbohydrate-based tolylsulfonyl hydrazines: effective catalysts for Michael addition of indoles to electron- deficient olefins in water. Synlett(2008), (8), 1193-1198.
6. Wu, Peng; Yi-qian Wan; Cai, Jiwen*. Carbohydrate-Based Tolylsulfonyl Hydrazines: Effective Catalysts for the Mannich Reaction and the Syntheses of Bisindolylalkanes in Water. Australian Journal of Chemistry (2008), 61(5), 359-363.
7. Gong Chen, Jiang Weng, Zhanchao Zheng , Xinhai Zhu,Yaoyao Cai, Jiwen Cai, Yi-qian Wan*，Pd/C Catalyzed Cyanation of Aryl halides in Aqueous PEG， Eur. J. Org. Chem., 2008 3524-28.
8. Gong Chen, Huanchen Wang, Howard Robinson, Jiwen Cai,Yi-qian Wan,*, Hengming Ke ,* An insight into the pharmacophores of phosphodiesterase-5 inhibitors from synthetic and crystal structural studies， Biochem Pharmacol，75 (2008) 1717-1728.
9. Wen, Huan; Lin, Chonglan; Ling, Que; Ge, Hui; Ma, Lin; Cao, Rihui; Yi-qian Wan; Peng, Wenlie; Wang, Zihou; Song, Huacan. Synthesis and biological evaluation of helicid analogues as novel acetylcholinesterase inhibitors.European Journal of Medicinal Chemistry (2008), 43(1), 166-173.
10. Liu, Jinbing; Yi, Wei; Yi-qian Wan; Ma, Lin; Song, Huacan. 1-(1-Arylethylidene) thiosemi- carbazide derivatives: A new class of tyrosinase inhibitors. Bioorg & Med Chem (2008), 16(3), 1096-1102.
11. 朱新海，陈功，许遵乐，万一千*，甲酸催化的室温无溶剂条件下利用Paal-Knorr反应合成吡咯衍生物的方法，有机化学，2008, 28(1), 115-119.
12. Pan, W.-L.; Tan, H.-B.; Chen, Y.; Mu, D.-H.; Liu, H.-B.; Yi-qian Wan.; Song, H.-C., The synthesis and preliminary optical study of 1-alkyl-2,4,5-triphenylimidazole derivatives. Dyes Pigm. 2008, 76, (1), 17-23.
13. Murugaiah, A. M. S.; Wallinder, C.; Mahalingam, A. K.; Wu, X.; Yi-qian Wan.; Plouffe, B.; Botros, M.; Karlen, A.; Hallberg, M.; Gallo-Payet, N.; Alterman, M., Selective angiotensin II AT2 receptor agonists devoid of the imidazole ring system. Bioorg. Med. Chem. 2007, 15, (22), 7166-7183
14. ZHU, Xin-Hai, CHEN, Gong, MA, Yan, SONG, Hua-Can, XU, Zun-Le, Yi-qian Wan* A General, Highly Efficient Ullmann C-O Coupling Reaction under Microwave Irradiation and the Effects of Water, Chinese Journal of Chemistry, 2007, 25, 546—552.
15. Pan, W.-l.; Xu, Y.-m.; Li, C.; Chen, Y.; Song, J.-g.; Xu, Z.-l.; Yi-qian Wan.; Song, H.-c., Synthesis and cation recognition of 1,1-bis(2-benzimidazolyl)-2-phenyl-ethylene derivatives as fluorescence receptors. 分析测试学报，2007, 26, (2), 160-164, 169.
16. Pan, W.-L.; Song, J.-G.; Chen, Y.; Yi-qian Wan.; Song, H.-C., Optical behaviors of conjugated-chain compounds containing benzene and furan units. Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy 2007, 66A, (4-5), 1300-1306.
17. Gong Chen, Xinhai Zhu, Jiwen Cai, Yi-qian Wan*, Palladium-free Copper-catalyzed coupling reaction of aryl iodides and terminal acetylenes in water, Synthetic Commun., 2007, 37: 1355–1361.
18. Xinhai Zhu, Yan Ma, Li Su, Huacan Song, Gong Chen, Dacheng Liang, Yi-qian Wan*, BCO/CuO-A Novel and Efficient Catalytic System for Ullmann-type C-N Coupling Reaction in Pure Water, Synthesis, (2006), (23), 3955-3962.
19. Xiongyu Wu, Yi-qian Wan, A. K. Mahalingam, A. M. S. Murugaiah, Bianca Plouffe, Milad Botros, Anders Karlen, Mathias Hallberg, Nicole Gallo-payet, and Mathias Alterman, Selective Angiotensin II AT2 Receptor Agonists: Arylbenzylimidazole Structure-Activity Relationships, Journal of Medicinal Chemistry 2006,49, 7160-7168.
20. Huang, Ji-Jun; Pan, Wen-Long; Yi-qian Wan; Song, Hua-Chan. Synthesis and crystal structure of tetramethyl 4aH-pyrido[1,2-a]quinoline-1,2,3,4-tetracarboxylate. 结构化学 (2006), 25(3), 348-352.
21. Pan, W.; Song, J.; Chen, Y.; Yu, W.; Wan Y.; Song, H., One-step Synthesis of 2-Benzimidazolyl Alkene under Microwave Irradiation, 明星色情小说
学报 （自科版）2006, 45, (6), 58-61.
22. Huang, J.; Pan, W.; Xiao, Q.; Feng, M.; Yi-qian Wan.; Ma, L.; Song, H., Synthesis, characterization and preliminary study of acetylcholinesterase inhibitory activity of 9aH-quinolizines. 明星色情小说
学报 （自科版）2006, 45, (3), 50-53.
23. Mahalingam, A. K.; Wu, Xiongyu; Yi-qian Wan; Alterman, Mathias. Scandium triflate as an efficient and recyclable catalyst for the deprotection of tert-butyl aryl sulfonamides. Synthetic Communications (2005), 35(3),417-425.
24. Chen, Chun-Long; Tan, Hai-Yan; Yao, Jun-Hua; Yi-qian Wan; Su, Cheng-Yong. Disilver(I) Rectangular-Shaped Metallacycles: X-ray Crystal Structure and Dynamic Behavior in Solution. Inorganic Chemistry (2005),44(23),8510-8520.
25. Yi-qian Wan; Wallinder, Charlotta; Plouffe, Bianca; Beaudry, Helene; Mahalingam, A. K.; Wu, Xiongyu; Johansson, Berndt;Holm, Mathias; Botoros, Milad; Karlen, Anders; Pettersson, Anders; Nyberg, Fred; Faendriks, Lars; Gallo-Payet, Nicole;Hallberg, Anders; Alterman, Mathias. Design, Synthesis, and Biological Evaluation of the First Selective Nonpeptide AT2 Receptor Agonist. Journal of Medicinal Chemistry (2004), 47(24), 5995-6008.
26. Alterman,Mathias; Mahalingam, Kannan; Hallberg, Anders; Yi-qian Wan; Mcneeney, Stephen Philip. (Vicore Pharma AB, Swed.). Preparation of azolylcarbonylphenylthiophenes and related compounds as angiotensin II agonists. PCT Int. Appl. (2004), 85 pp. CODEN: PIXXD2 WO 2004046141 A1 20040603. Designated States W: AE, AG, AL,AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI,GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK,MN, MW, MX, MZ, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ,UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW. Designated States RW: AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR,IE, IT, LU, MC, NL, PT, SE, TR, BF, BJ, CF, CG, CI, CM, GA, ML, MR, NE, SN, TD, TG. Patent written in English.Application: WO 2003-GB5037 20031119. Priority: US 2002-427936 20021121. CAN 141:23524 AN 2004:453212
27. Alterman, Mathias; Hallberg, Anders; Yi-qian Wan; Mahalingam, Kannan; Mcneeney, Stephen Phillip. (Vicore Pharma AB, Swed.). A preparation of novel thiophene derivatives, useful as angiotensin II receptor agonists. PCT Int.Appl. (2004), 64 pp. CODEN: PIXXD2 WO 2004046137 A1 20040603 Designated States W: AE, AG, AL, AM, AT,AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD,GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW,MX, MZ, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG,US, UZ, VC, VN, YU, ZA, ZM, ZW. Designated States RW: AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU,MC, NL, PT, SE, TR, BF, BJ, CF, CG, CI, CM, GA, ML, MR, NE, SN, TD, TG. Patent written in English. Application:WO 2003-GB5013 20031119. Priority: US 2002-427942 20021121. CAN 141:7115 AN 2004:453209
28. Wu, Xiongyu; Mahalingam, A. K.; Yi-qian Wan; Alterman, Mathias. Fast microwave-promoted palladium-catalyzed synthesis of phthalides from bromobenzyl alcohols utilizing DMF and Mo(CO)6 as carbon monoxide sources. Tetrahedron Letters(2004), 45(24), 4635-4638.
29. Yi-qian Wan; Wallinder, Charlotta; Johansson, Berndt; Holm, Mathias; Mahalingam, A. K.; Wu, Xiongyu; Botros, Milad; Karlen,Anders; Pettersson, Anders; Nyberg, Fred; Faendriks, Lars; Hallberg, Anders; Alterman, Mathias. First Reported Nonpeptide AT1 Receptor Agonist (L-162,313) Acts as an AT2 Receptor Agonist in Vivo. Journal of Medicinal Chemistry (2004), 47(6), 1536-1546.
30. Yi-qian Wan; Wu, Xiongyu; Kannan, Mahalingam A.; Alterman, Mathias. Boron trichloride as an efficient and selective agent for deprotection of tert-butyl aryl sulfonamides. Tetrahedron Letters (2003), 44(24), 4523-4525.）
31. Yi-qian Wan; Alterman, Mathias; Larhed, Mats; Hallberg, Anders. Formamide as a Combined Ammonia Synthon and Carbon Monoxide Source in Fast Palladium-Catalyzed Aminocarbonylations of Aryl Halides. Journal of Combinatorial Chemistry (2003), 5(2), 82-84.
32. Larhed, Mats; Alterman,Mathias; Yi-qian Wan; Hallberg, Anders; Kaiser, Nils-Fredrik. (Swed.). One-pot carbonylation reaction with metal carbonyl as carbon monoxide source. U.S. Pat. Appl. Publ. (2002), 23 pp. US 2002161266 A1 20021031 Patent written in English. Application: US 2001-14562 20011214.Priority: US 2000-255143 20001214. CAN 137:337460 AN 2002:833570.
33. Yi-qian Wan; Alterman, Mathias; Hallberg, Anders. Palladium-catalyzed amination of aryl bromides using temperature-controlled microwave heating. Synthesis (2002), (11), 1597-1600.
34. Yi-qian Wan; Alterman, Mathias; Larhed, Mats; Hallberg, Anders. Dimethylformamide as a Carbon Monoxide Source in Fast Palladium-Catalyzed Aminocarbonylations of ArylBromides. Journal of Organic Chemistry (2002), 67(17), 6232-6235.
35. Kaiser, Nils-Fredrik; Larhed, Mats; Hallberg, Anders; Alterman, Mathias; Yi-qian Wan. (Personal Chemistry I Uppsala AB, Swed.). One-pot carbonylation reaction with metal carbonyl as carbon monoxide source. PCT Int. Appl.(2002), 48 pp. CODEN: PIXXD2 WO 2002048072 A2 20020620 Designated States W: AE, AG, AL, AM, AT, AU,AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, ES, FI, GB, GD, GE, GH, GM,HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO,NZ, OM, PH, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZM,ZW, AM, AZ, BY, KG, KZ, MD, RU, TJ, TM. Designated States RW: AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, TR, BF, BJ, CF, CG, CI, CM, GA, ML, MR, NE, SN, TD, TG. Patent written in English. Application: WO 2001-EP14596 20011212. Priority: DK 2000-1879 20001214. CAN 137:32955 AN 2002:465945
36. Sarvary, Ian; Yi-qian Wan; Frejd, Torbjorn. Novel cyclic and bicyclic 1,3-diols as catalysts for diethylzinc addition to aldehydes. Journal of the Chemical Society, Perkin Transactions 1 (2002), (5), 645-651.
37. 万一千，苏镜娱 ，曾陇梅等，A Convergent Synthesis of (E,E,E)-3,7,13-trimethl-6-(I-propenyl)-7,14-Dihydroxy-2,8,12-tetradecatrien-1- Methylal, Chinese Chemical Letters(Eng), 1996, 7(2), 109-110.
38. 万一千，苏镜娱，曾陇梅，海绵Phyllospongia sp.中的两种新的 Scalarane-型二倍半萜，高等学校化学学报，1996, 17(11), 1747-1749.
39. 万一千，曾志， 曾陇梅，软珊瑚Labophytum catelai的甾类化合物研究，明星色情小说
学报，1996, vol.35（增）, 171-172.
40. 万一千，苏镜娱， 曾陇梅，海绵Spongia officinalis的化学成分研究，中国海洋药物，1997, 16(1), 1-3.
41. 万一千，苏镜娱，曾陇梅. Chemical Study on the Marine Sponge Phyllospongia sp., Book of Abstracts for Fifth Eurasia Conference on Chemical Sciences, pp316, Zhongshan university press, 1996, Guangzhou.
42. 万一千，苏镜娱，曾陇梅，海绵Phyllospongia sp.的代谢物研究 (2)，明星色情小说
学报，1997, 36(1), 116-118.
43. 万一千，刘青，软珊瑚Labophytum catelai的化学成分研究（I），热带海洋，1997,16(3), 78-82.
44. 万一千，苏镜娱，曾陇梅，Ceramide from the Marine Sponge Phyllospongia sp., Acta Scientiarum Naturalium Universitatis zhongshan (Sun-Yatsenz), 1997, 36(5), 113-115.
45. 万一千，刘青，曾陇梅，苏镜娱，The Secondary Metabolites of Marine Sponge Phyllospongia foliascens, 明星色情小说
学报, 1998, 37(3), 81~84.
46. 曾陇梅，杨善淼, 苏镜娱，吴建青，万一千，包工藤甲素全合成的研究(II)，高等学校化学学报，1998, 19(5), 737-740.
47. 晏日安，万一千，环柠檬醛合成方法改进，化学世界，1998, 4, 173-174.
48. 曾志，曾陇梅，万一千，甾醇的质谱学裂解规律（3），质谱学报，1996, 17(4), 13
49. 官智，何延红，万一千，反相硅胶的简便制备方法，化学通报 1998, (12), 57.
50. 万一千，苏镜娱，曾陇梅，刘青，符雄，海绵Phyllospongia foliascens中的两个新的二倍半萜，海洋可持续发展论文集，161, 海洋出版社，1998, 北京.
51. 万一千，苏镜娱，曾陇梅，海绵Phyllospongia sp.的化学成分研究，97海岸海洋资源与环境学术研讨会论文集，258，香港科技大学出版.
52. 万一千，周秀中，刘伟文； 1,1'-(四甲二硅基) 双[环戊二烯基钨的合成]，南开大学学报（自然科学版），1994, 4, 94.
相关成果
1. 万一千，朱新海，王金龙，陈功，马彦，宋化灿，许遵乐，二芳基醚的水热合成法，中国发明专利，公开号：CN 1680244A
2. 万一千，朱新海，马彦，陈功，宋化灿，苏丽，以酰腙为配体的水相体系中N-芳基化方法，中国发明专利，公开号：CN 1803760 A
3. 万一千，朱新海，陈功，苏丽，宋化灿，梁大成，一种水溶液中的N-芳基化方法，中国发明专利，公开号：CN 101012170A。
4. 宋化灿，黄计军，万一千，张淑华，王子厚，明星色情小说
2,6-二氨基-,3,5-二氰基-4-芳基吡啶衍生物的合成方法与应用，公开号：CN1887871A。
5. 万一千，陈功，柯衡明，蔡继文， Preparation and application of pyrazolopyrimidinone derivate. 中国发明专利，公开号：CN101279974A
